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Article

A polymorphism in FAS gene promoter correlated with circulating soluble FAS levels.

International journal of immunogenetics - 1 Jun 2007

Mahfoudh W, Bel Hadj Jrad B, Romdhane A, Chouchane L

Abstract excerpt

The -670FAS (A/G) polymorphism and elevated concentrations of the soluble form of FAS (sFAS) have been associated with neoplasic and autoimmune diseases. This polymorphism in the Fas promoter gene could modulate the transcription of Fas expression and therefore, contribute to these pathologies. The in vivo functional significance of the FAS polymorphism was investigated by assessing the correlation between FAS...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17504511
DOI: 10.1111/j.1744-313X.2007.00676.x

Genes

FAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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