Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification and characterization of polymorphisms in the promoter region of the human Apo-1/Fas (CD95) gene.

Molecular immunology - 1 Jun 1997

Huang Q R, Morris D, Manolios N

Abstract excerpt

Apo-1/Fas (CD95) is a transmembrane protein expressed on the cell surface that is involved in apoptosis and plays an important role in the function and regulation of the immune system. Aberrant expression of the Apo-1/Fas gene product has been reported in a number of immune-related disorders, such as autoimmune lymphoproliferative syndrome and systemic lupus erythematosus in humans. Mutations in the coding...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apoptosis
Share to Base Sequence
Share to Gene Expression

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotype

Share to Molecular Sequence Data

Share to Polymorphism, Restriction Fragment Length

Share to Polymorphism, Single-Stranded Conformational

Share to Promoter Regions, Genetic

Source

Identifiers

PMID: 9393960
DOI: 10.1016/s0161-5890(97)00081-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification and characterization of polymorphisms in the promoter region of the human Apo-1/Fas (CD95) gene.PMID 9393960Read ↗

Structure of the human APO‐1 geneSemantic proximity Read ↗

Investigation of the -1377 polymorphism on the Apo-1/Fas promoter in systemic lupus erythematosus patients using allele-specific amplification.Semantic proximity Read ↗

A functional polymorphism in fas (CD95/APO-1) gene promoter associated with systemic lupus erythematosus.Semantic proximity Read ↗

Functional FAS promoter polymorphisms are associated with increased risk of acute myeloid leukemia.Semantic proximity Read ↗

Association of FAS gene polymorphisms with systemic lupus erythematosus: A case-control study and meta-analysisSemantic proximity Read ↗

The -844C/T polymorphism in the Fas ligand promoter associates with Taiwanese SLE.Semantic proximity Read ↗

Evaluation of a Apo-1/Fas promoter polymorphism in Korean stroke patients.Semantic proximity Read ↗

The FAS/cd95 promoter single-nucleotide polymorphism -670 A/G and lupus erythematosus.Semantic proximity Read ↗

Association of FAS and FAS ligand genes polymorphism and risk of systemic lupus erythematosus.Semantic proximity Read ↗

Assignment of the human fas antigen gene (FAS) to 10q24.1Semantic proximity Read ↗

The molecular basis for apoptotic defects in patients with CD95 (Fas/Apo-1) mutations.Semantic proximity Read ↗

Complete molecular scanning of the human Fas gene: mutational analysis and linkage studies in families with type I diabetes mellitus. The Danish Study Group of Diabetes in Childhood and The Danish IDDM Epidemiology and Genetics Group.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.