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Article

The FAS/cd95 promoter single-nucleotide polymorphism -670 A/G and lupus erythematosus.

Clinical and experimental dermatology - 1 Jun 2012

Molin S, Weiss E H, Ruzicka T, Messer G

Abstract excerpt

An increased level of circulating nuclear antigens caused by apoptosis is thought to be responsible for the production of autoantibodies in lupus erythematosus (LE). The presentation of these antigens to immunologically competent cells may trigger systemic autoimmunity. The influence of a functional single-nucleotide polymorphism at position -670 in the promoter of the apoptosis gene FAS on susceptibility to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22299671
DOI: 10.1111/j.1365-2230.2011.04296.x

Genes

FAS

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The FAS/cd95 promoter single-nucleotide polymorphism -670 A/G and lupus erythematosus.PMID 22299671Read ↗

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Fas promoter -670 polymorphism is associated with development of anti-RNP antibodies in systemic lupus erythematosus.Semantic proximity Read ↗

A functional polymorphism in fas (CD95/APO-1) gene promoter associated with systemic lupus erythematosus.Semantic proximity Read ↗

Association of FAS and FAS ligand genes polymorphism and risk of systemic lupus erythematosus.Semantic proximity Read ↗

The -670G>A polymorphism in the FAS gene promoter region influences the susceptibility to systemic sclerosis.Semantic proximity Read ↗

Associations between the FAS -670 A/G, -1377 G/A, and FASL -844 T/C polymorphisms and susceptibility to systemic lupus erythematosus: a meta-analysis.Semantic proximity Read ↗

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Identification and characterization of polymorphisms in the promoter region of the human Apo-1/Fas (CD95) gene.Semantic proximity Read ↗

Evaluation of polymorphic variants in apoptotic genes and their role in susceptibility and clinical progression to systemic lupus erythematosus.Semantic proximity Read ↗

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