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Article

Evaluation of offspring and maternal genetic effects on disease risk using a family-based approach: the "pent" design.

American journal of epidemiology - 1 Oct 2005

Mitchell Laura E, Weinberg Clarice R

Abstract excerpt

Diseases that develop during gestation may be influenced by the genotype of the mother and the inherited genotype of the embryo/fetus. However, given the correlation between maternal and offspring genotypes, differentiating between inherited and maternal genetic effects is not straightforward. The two-step transmission disequilibrium test was the first, family-based test proposed for the purpose of...

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Identifiers

PMID: 16093287
DOI: 10.1093/aje/kwi249

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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