Article
Gene-environment interplay in common complex diseases: forging an integrative model—recommendations from an NIH workshop.
Genetic epidemiology - 1 May 2011
Bookman Ebony B, McAllister Kimberly, Gillanders Elizabeth, Wanke Kay, Balshaw David, Rutter Joni, Reedy Jill, Shaughnessy Daniel, Agurs-Collins Tanya, Paltoo Dina, Atienza Audie, Bierut Laura, Kraft Peter, Fallin M Daniele, Perera Frederica, Turkheimer Eric, Boardman Jason, Marazita Mary L, Rappaport Stephen M, Boerwinkle Eric, Suomi Stephen J, Caporaso Neil E, Hertz-Picciotto Irva, Jacobson Kristen C, Lowe William L, Goldman Lynn R, Duggal Priya, Gunnar Megan R, Manolio Teri A, Green Eric D, Olster Deborah H, Birnbaum Linda S
Abstract excerpt
Although it is recognized that many common complex diseases are a result of multiple genetic and environmental risk factors, studies of gene-environment interaction remain a challenge and have had limited success to date. Given the current state-of-the-science, NIH sought input on ways to accelerate investigations of gene-environment interplay in health and disease by inviting experts from a variety of...
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