Article
Epidemiological methods for studying genes and environmental factors in complex diseases.
Lancet (London, England) - 20 Oct 2001
Clayton D, McKeigue P M
Abstract excerpt
Exploration of the human genome presents new challenges and opportunities for epidemiological research. Although the case-control design is quicker and cheaper for study of associations between genotype and risk of disease than the cohort design, cohort studies have been recommended because they can be used to study gene-environment interactions. Although the scientific relevance of statistical interaction is...
Topics
- Case-Control Studies
- Environmental Exposure
- Epidemiology
- Female
- Genetics, Medical
- Genotype
- Humans
- Research Design
- Risk Factors
- Venous Thrombosis