Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Microphakia and congenital cataract formation in a novel Lim2(C51R) mutant mouse.

Molecular vision - 1 Jan 2011

Puk Oliver, Ahmad Nafees, Wagner Sibylle, de Angelis Martin Hrabé, Graw Jochen

Abstract excerpt

PURPOSE: Within a mutagenesis screen, we identified the new mouse mutant Aca47 with small lenses and reduced axial eye lengths. The aim of the actual study was the molecular and morphological characterization of the mouse mutant Aca47. METHODS: We analyzed the offspring of paternally N-ethyl-N-nitrosourea (ENU) treated C57BL/6J mice for eye-size parameters by non-invasive in vivo laser interference biometry....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cataract
Share to Ethylnitrosourea
Share to Eye

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Eye Proteins

Share to Founder Effect

Share to Lens, Crystalline

Share to Membrane Glycoproteins

Share to Microphthalmos

Source

Open in PubMed Open full text

Identifiers

PMID: 21617753
PMCID: PMC3102026

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Microphakia and congenital cataract formation in a novel Lim2(C51R) mutant mouse.PMID 21617753Read ↗

The pathologic effect of a novel neomorphic Fgf9(Y162C) allele is restricted to decreased vision and retarded lens growth.Semantic proximity Read ↗

Reduced corneal thickness and enlarged anterior chamber in a novel ColVIIIa2G257D mutant mouse.Semantic proximity Read ↗

First mutation in the βA2-crystallin encoding gene is associated with small lenses and age-related cataracts.Semantic proximity Read ↗

A new Fgf10 mutation in the mouse leads to atrophy of the harderian gland and slit-eye phenotype in heterozygotes: a novel model for dry-eye disease?Semantic proximity Read ↗

Saturation mutagenesis for dominant eye morphological defects in the mouse Mus musculus.Semantic proximity Read ↗

Novel ENU-induced eye mutations in the mouse: models for human eye disease.Semantic proximity Read ↗

Mouse models for microphthalmia, anophthalmia and cataractsSemantic proximity Read ↗

Novel small-eye allele in paired box gene 6 (Pax6) is caused by a point mutation in intron 7 and creates a new exon.Semantic proximity Read ↗

Aphakia (ak), a mouse mutation affecting early eye development: fine mapping, consideration of candidate genes and altered Pax6 and Six3 gene expression pattern.Semantic proximity Read ↗

Congenital hereditary cataracts.Semantic proximity Read ↗

Cataract mutations and lens development.Semantic proximity Read ↗

Missense Mutations in the Human Nanophthalmos Gene <i>TMEM98</i> Cause Retinal Defects in the MouseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.