Article
Juvenile cystic kidneys (jck): a new mouse mutation which causes polycystic kidneys.
Kidney international - 1 May 1993
Atala A, Freeman M R, Mandell J, Beier D R
Abstract excerpt
We have characterized a new recessive mutation in the mouse which predisposes to the development of polycystic kidney disease. This mutation, called juvenile cystic kidneys (jck), arose in a transgenic line of mice, but appears unrelated to the transgene since it segregates freely from it. While focal cysts are evident in affected animals as early as three days of life and the disease is progressive, the mice are...
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