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Article

Regional variation in the density of essential genes in mice.

PLoS genetics - 4 May 2007

Hentges Kathryn E, Pollock David D, Liu Bin, Justice Monica J

Abstract excerpt

In most species, and particularly in vertebrates, the percentage of genes absolutely required for survival, the essential genes, has not been estimated. To obtain this estimation, we used the mouse as an experimental model to carry out high-efficiency N-ethyl-N-nitrosourea (ENU) mutagenesis scree...

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PMID: 17480122
DOI: 10.1371/journal.pgen.0030072
PMCID: PMC1865562

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17480122-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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