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Article

Regional variation in the density of essential genes in mice.

PLoS genetics - 4 May 2007

Hentges Kathryn E, Pollock David D, Liu Bin, Justice Monica J

Abstract excerpt

In most species, and particularly in vertebrates, the percentage of genes absolutely required for survival, the essential genes, has not been estimated. To obtain this estimation, we used the mouse as an experimental model to carry out high-efficiency N-ethyl-N-nitrosourea (ENU) mutagenesis screens in two balancer chromosome regions, and compared our results to a third previously published screen. The number of...

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Identifiers

PMID: 17480122
DOI: 10.1371/journal.pgen.0030072
PMCID: PMC1865562

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Source receipt: pubmed, retrieved 7 Sept 2026.

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