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Article

Identification of the imprinted KLF14 transcription factor undergoing human-specific accelerated evolution.

PLoS genetics - 4 May 2007

Parker-Katiraee Layla, Carson Andrew R, Yamada Takahiro, Arnaud Philippe, Feil Robert, Abu-Amero Sayeda N, Moore Gudrun E, Kaneda Masahiro, Perry George H, Stone Anne C, Lee Charles, Meguro-Horike Makiko, Sasaki Hiroyuki, Kobayashi Keiko, Nakabayashi Kazuhiko, Scherer Stephen W

Abstract excerpt

Imprinted genes are expressed in a parent-of-origin manner and are located in clusters throughout the genome. Aberrations in the expression of imprinted genes on human Chromosome 7 have been suggested to play a role in the etiologies of Russell-Silver Syndrome and autism. We describe the imprinting of KLF14, an intronless member of the Krüppel-like family of transcription factors located at Chromosome 7q32. We...

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Source

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Identifiers

PMID: 17480121
DOI: 10.1371/journal.pgen.0030065
PMCID: PMC1865561

Genes

KLF14

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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