Article
Conservation and divergence of canonical and non-canonical imprinting in murids.
Genome biology - 14 Mar 2023
Richard Albert Julien, Kobayashi Toshihiro, Inoue Azusa, Monteagudo-Sánchez Ana, Kumamoto Soichiro, Takashima Tomoya, Miura Asuka, Oikawa Mami, Miura Fumihito, Takada Shuji, Hirabayashi Masumi, Korthauer Keegan, Kurimoto Kazuki, Greenberg Maxim V C, Lorincz Matthew, Kobayashi Hisato
Abstract excerpt
BACKGROUND: Genomic imprinting affects gene expression in a parent-of-origin manner and has a profound impact on complex traits including growth and behavior. While the rat is widely used to model human pathophysiology, few imprinted genes have been identified in this murid. To systematically identify imprinted genes and genomic imprints in the rat, we use low input methods for genome-wide analyses of gene...
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