Article
Structure and function correlations at the imprinted mouse Snrpn locus.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Oct 1998
Gabriel J M, Gray T A, Stubbs L, Saitoh S, Ohta T, Nicholls R D
Abstract excerpt
The human SNRPN gene maps within Chromosome (Chr) 15q11-q13, the region responsible for Prader-Willi syndrome (PWS) and Angelman syndrome (AS). As one of several 15q11-q13 transcripts expressed from the paternal allele-only, SNRPN is a candidate gene to explain at least some of the PWS phenotype...
Topics
- Angelman Syndrome
- Animals
- Autoantigens
- Chromosome Mapping
- Chromosomes, Human, Pair 15
- Cloning, Molecular
- Conserved Sequence
- DNA Methylation
- DNA Primers
- DNA, Complementary
- Disease Models, Animal
- Exons
- Female
- Genomic Imprinting
- Humans
- Male
- Mice
- Molecular Sequence Data