Article
CARD15 genotype and phenotype analysis in 55 pediatric patients with Crohn disease from Saxony, Germany.
Journal of pediatric gastroenterology and nutrition - 1 Oct 2003
Sun Liping, Roesler Joachim, Rösen-Wolff Angela, Winkler Ulf, Koch Rainer, Thürigen Anett, Henker Jobst
Abstract excerpt
OBJECTIVES: Crohn disease is a chronic inflammatory bowel disorder that is caused by environmental and genetic factors. Mutations in the CARD15 gene have been recently identified to be associated with the disease. Until now no genetic study has focused directly on a pediatric population. METHODS: The authors sequenced all 12 exons of the CARD15 gene in 55 pediatric patients with Crohn disease from Saxony. Their...
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