Article
A knockout mouse approach reveals that TCTP functions as an essential factor for cell proliferation and survival in a tissue- or cell type-specific manner.
Molecular biology of the cell - 1 Jul 2007
Chen Sung Ho, Wu Peih-Shan, Chou Chiang-Hung, Yan Yu-Ting, Liu Hsuan, Weng Shih-Yen, Yang-Yen Hsin-Fang
Abstract excerpt
Translationally controlled Tumor Protein (TCTP) is an evolutionally highly conserved protein which has been implicated in many cellular functions that are related to cell growth, death, and even the allergic response of the host. To address the physiological roles of TCTP, we generated TCTP knock...
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