Article
Tumor Suppressors in Zebrafish: From TP53 to PTEN and Beyond.
Advances in experimental medicine and biology - 1 Jan 2016
den Hertog Jeroen
Abstract excerpt
Zebrafish are increasingly being used to study cancer. Almost all tumor types have been found in zebrafish. However, tumor incidence is relatively low and tumors develop late in life. Functional inactivation of tumor suppressors is a crucial step in cancer progression and more and more tumor suppressor genes are being studied in zebrafish. Most often tumor suppressors have been inactivated by reverse genetics...
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