Article
TCTP is Essential for Cell Proliferation and Survival during CNS Development.
Cells - 6 Jan 2020
Chen Sung-Ho, Lu Chin-Hung, Tsai Ming-Jen
Abstract excerpt
Translationally controlled tumor-associated protein (TCTP) has been implicated in cell growth, proliferation, and apoptosis through interacting proteins. Although TCTP is expressed abundantly in the mouse brain, little is known regarding its role in the neurogenesis of the nervous system. We used Nestin-cre-driven gene-mutated mice to investigate the function of TCTP in the nervous system. The mice carrying...
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