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Article

Association of Mycobacterium tuberculosis PE PGRS33 polymorphism with clinical and epidemiological characteristics.

Tuberculosis (Edinburgh, Scotland) - 1 Jul 2007

Talarico Sarah, Cave M Donald, Foxman Betsy, Marrs Carl F, Zhang Lixin, Bates Joseph H, Yang Zhenhua

Abstract excerpt

There is evidence that some members of the Mycobacterium tuberculosis PE PGRS gene subfamily, including PE PGRS33, may have a specific function in M. tuberculosis persistence. The impact of naturally-occurring PE PGRS33 genetic variations on the virulence and transmissibility of clinical M. tuberculosis isolates is not known. We used PCR and DNA sequencing to identify genetic variations in the PE PGRS33 gene in...

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Identifiers

PMID: 17475562
DOI: 10.1016/j.tube.2007.03.003
PMCID: PMC2093954

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