Article
Variation of the Mycobacterium tuberculosis PE_PGRS 33 gene among clinical isolates.
Journal of clinical microbiology - 1 Oct 2005
Talarico Sarah, Cave M Donald, Marrs Carl F, Foxman Betsy, Zhang Lixin, Yang Zhenhua
Abstract excerpt
PE_PGRS 33, one of about 60 PE_PGRS genes in the Mycobacterium tuberculosis genome, encodes a surface-expressed protein that may be involved in the antigenic variation of M. tuberculosis strains and evasion of the host immune system. While genetic differences between the PE_PGRS 33 genes of H37Rv and CDC 1551 have been noted, genetic variation in this gene among clinical isolates has not been evaluated. In order...
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