Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

PE/PPE mutations in the transmission of Mycobacterium tuberculosis in China revealed by whole genome sequencing.

BMC microbiology - 10 Jun 2024

Fang Wei-Wei, Kong Xiang-Long, Yang Jie-Yu, Tao Ning-Ning, Li Ya-Meng, Wang Ting-Ting, Li Ying-Ying, Han Qi-Lin, Zhang Yu-Zhen, Hu Jin-Jiang, Li Huai-Chen, Liu Yao

Abstract excerpt

OBJECTIVE: This study aims to examine the impact of PE/PPE gene mutations on the transmission of Mycobacterium tuberculosis (M. tuberculosis) in China. METHODS: We collected the whole genome sequencing (WGS) data of 3202 M. tuberculosis isolates in China from 2007 to 2018 and investigated the clustering of strains from different lineages. To evaluate the potential role of PE/PPE gene mutations in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Proteins
Share to China

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome, Bacterial

Share to Mutation

Share to Mycobacterium tuberculosis

Share to Polymorphism, Single Nucleotide

Share to Tuberculosis

Share to Whole Genome Sequencing

Source

Open in PubMed Open full text

Identifiers

PMID: 38858614
DOI: 10.1186/s12866-024-03352-y
PMCID: PMC11163795

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

PE/PPE mutations in the transmission of Mycobacterium tuberculosis in China revealed by whole genome sequencing.PMID 38858614Read ↗

Analysis of complete genomes of Mycobacterium tuberculosis sublineage 2.1 (Proto-Beijing) revealed the presence of three pe_pgrs3-pe_pgrs4-like genes.Semantic proximity Read ↗

Functional genetic variation in pe/ppe genes contributes to diversity in Mycobacterium tuberculosis lineages and potential interactions with the human hostSemantic proximity Read ↗

Association between two-component systems gene mutation and Mycobacterium tuberculosis transmission revealed by whole genome sequencing.Semantic proximity Read ↗

Pan- and core genome analysis of Mycobacterium tuberculosis in high-resolution transmission and genetic diversity studies.Semantic proximity Read ↗

Homoplastic single nucleotide polymorphisms contributed to phenotypic diversity in Mycobacterium tuberculosis.Semantic proximity Read ↗

Multi-platform whole genome sequencing for tuberculosis clinical and surveillance applicationsSemantic proximity Read ↗

The Bioinformatics Analysis of Comparative Genomics of Mycobacterium tuberculosis Complex (MTBC) Provides Insight into Dissimilarities between Intraspecific Groups Differing in Host Association, Virulence, and Epitope DiversitySemantic proximity Read ↗

Characterization of genomic variations in SNPs of PE_PGRS genes reveals deletions and insertions in extensively drug resistant (XDR) M. tuberculosis strains from Pakistan.Semantic proximity Read ↗

Transmission and resistome of extremely drug-resistant tuberculosis in Beijing, China: A retrospective population-based epidemiological study.Semantic proximity Read ↗

Pangenome Reconstruction of Mycobacterium tuberculosis as a Guide to Reveal Genomic Features Associated with Strain Clinical PhenotypeSemantic proximity Read ↗

Recombination in pe/ppe genes contributes to genetic variation in Mycobacterium tuberculosis lineages.Semantic proximity Read ↗

Pan-Genomic Study of Mycobacterium tuberculosis Reflecting the Primary/Secondary Genes, Generality/Individuality, and the Interconversion Through Copy Number VariationsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.