Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

PE_PGRS33 Contributes to Mycobacterium tuberculosis Entry in Macrophages through Interaction with TLR2

15 Mar 2016

Abstract excerpt

PE_PGRS represent a large family of proteins typical of pathogenic mycobacteria whose members are characterized by an N-terminal PE domain followed by a large Gly-Ala repeat-rich C-terminal domain. Despite the abundance of PE_PGRS-coding genes in the Mycobacterium tuberculosis (Mtb) genome their role and function in the biology and pathogenesis still remains elusive. In this study, we generated and characterized...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mycobacterium research and diagnosis
Share to Pneumocystis jirovecii pneumonia detection and treatment
Share to Tuberculosis Research and Epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26978522
DOI: 10.1371/journal.pone.0150800

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

PE_PGRS33 Contributes to Mycobacterium tuberculosis Entry in Macrophages through Interaction with TLR2PMID 26978522Read ↗

Functional dissection of protein domains involved in the immunomodulatory properties of PE_PGRS33 of Mycobacterium tuberculosis.Semantic proximity Read ↗

PE_PGRS30 is required for the full virulence of Mycobacterium tuberculosisSemantic proximity Read ↗

PE_PGRS33, an Important Virulence Factor of Mycobacterium tuberculosis and Potential Target of Host Humoral Immune Response.Semantic proximity Read ↗

Impact of pe_pgrs33 Gene Polymorphisms on Mycobacterium tuberculosis Infection and Pathogenesis.Semantic proximity Read ↗

Mycobacterium tuberculosis PE_PGRS41 Enhances the Intracellular Survival of M. smegmatis within Macrophages Via Blocking Innate Immunity and Inhibition of Host DefenseSemantic proximity Read ↗

Impact of Protein Domains on PE_PGRS30 Polar Localization in MycobacteriaSemantic proximity Read ↗

Functional dissection of the PE domain responsible for translocation of PE_PGRS33 across the mycobacterial cell wall.Semantic proximity Read ↗

PE_PGRS proteins ofMycobacterium tuberculosis: A specialized molecular task force at the forefront of host–pathogen interactionSemantic proximity Read ↗

An overview to understand the role of PE _ PGRS family proteins in M ycobacterium tuberculosis H 37 R v and their potential as new drug targetsSemantic proximity Read ↗

Rv1818c‐encoded PE_PGRS protein of <i>Mycobacterium tuberculosis</i> is surface exposed and influences bacterial cell structureSemantic proximity Read ↗

PE_PGRS62 promotes the survival of Mycobacterium smegmatis within macrophages via disrupting ER stress‐mediated apoptosisSemantic proximity Read ↗

Evidence that mycobacterial PE_PGRS proteins are cell surface constituents that influence interactions with other cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.