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Article

Identification and phenotypic characterization of a beta-lactam-dependent, methicillin-resistant Staphylococcus aureus strain.

Antimicrobial agents and chemotherapy - 1 Jul 2007

Goldstein Fred, Perutka Jiri, Cuirolo Arabela, Plata Konrad, Faccone Diego, Morris Joanne, Sournia Aude, Kitzis Marie Dominique, Ly Aicha, Archer Gordon, Rosato Adriana E

Abstract excerpt

Methicillin resistance in Staphylococcus aureus is primarily mediated by the acquired penicillin-binding protein PBP 2a, which is encoded by mecA. PBP 2a acts together with native PBP 2 to mediate oxacillin resistance by contributing complementary transpeptidase and transglycosylase activities, respectively. In this study, we have investigated a phenotype of beta-lactam dependence in a clinical...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 17470657
DOI: 10.1128/AAC.00040-07
PMCID: PMC1913265

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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