Article

Methicillin resistance in staphylococci: molecular and biochemical basis and clinical implications.

1997-01-01

Abstract excerpt

Methicillin resistance in staphylococci is determined by mec, composed of 50 kb or more of DNA found only in methicillin-resistant strains. mec contains mecA, the gene for penicillin-binding protein 2a (PBP 2a); mecI and mecR1, regulatory genes controlling mecA expression; and numerous other elements and resistance determinants. A distinctive feature of methicillin resistance is its heterogeneous expression. Borde...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 273bd29f-b0df-5f0c-aa92-ece1682c2294
DOI: 10.1128/cmr.10.4.781-791.1997

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Methicillin resistance in staphylococci: molecular and biochemical basis and clinical implications.DOI 10.1128/cmr.10.4.781-791.1997Read

Methicillin resistance in staphylococci: molecular and biochemical basis and clinical implicationsSemantic proximity Read

Molecular mechanisms of methicillin resistance in Staphylococcus aureus.Semantic proximity Read

Mechanisms of Methicillin Resistance in <i>Staphylococcus aureus</i>Semantic proximity Read

Methicillin resistance in Staphylococcus aureus and coagulase-negative staphylococci: epidemiological and molecular aspects.Semantic proximity Read

Microbiological Characteristics of Methicillin-resistant Staphylococcus aureusSemantic proximity Read

Methicillin Resistance in Staphylococcus Aureus: Mechanisms and ModulationSemantic proximity Read

An Achilles' heel for methicillin-resistant Staphylococcus aureus? Re-evaluating β-lactam susceptibility of MRSA.Semantic proximity Read

Novel mutations in penicillin-binding protein genes in clinical Staphylococcus aureus isolates that are methicillin resistant on susceptibility testing, but lack the mec geneSemantic proximity Read

Absence of meca gene in methicillin-resistant staphylococcus aureus isolatesSemantic proximity Read

Key Genetic Elements and Regulation Systems in Methicillin-Resistant <i>Staphylococcus Aureus</i>Semantic proximity Read

Staphylococcal chromosomal cassettes mec (SCCmec): A mobile genetic element in methicillin-resistant Staphylococcus aureus.Semantic proximity Read

Mutation-Based Antibiotic Resistance Mechanism in Methicillin-Resistant Staphylococcus aureus Clinical IsolatesSemantic proximity Read