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Article

Evidence of a novel staphylococcal mec-encoded element (mecR) controlling expression of penicillin-binding protein 2'.

Antimicrobial agents and chemotherapy - 1 Sept 1990

Tesch W, Ryffel C, Strässle A, Kayser F H, Berger-Bächi B

Abstract excerpt

A region was identified on the methicillin resistance determinant (mec) isolated from Staphylococcus epidermidis and cloned into Staphylococcus carnosus which was responsible for a novel downregulation of the expression of methicillin resistance. The presence of this region reduced the overall expression of methicillin resistance and the synthesis of the mec-encoded penicillin-binding protein 2' (PBP 2') in S....

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Identifiers

PMID: 2285282
DOI: 10.1128/AAC.34.9.1703
PMCID: PMC171909

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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