Article
Evidence of a novel staphylococcal mec-encoded element (mecR) controlling expression of penicillin-binding protein 2'.
Antimicrobial agents and chemotherapy - 1 Sept 1990
Tesch W, Ryffel C, Strässle A, Kayser F H, Berger-Bächi B
Abstract excerpt
A region was identified on the methicillin resistance determinant (mec) isolated from Staphylococcus epidermidis and cloned into Staphylococcus carnosus which was responsible for a novel downregulation of the expression of methicillin resistance. The presence of this region reduced the overall ex...
Topics
- Bacterial Proteins
- Carrier Proteins
- DNA, Bacterial
- Gene Expression
- Hexosyltransferases
- Methicillin Resistance
- Muramoylpentapeptide Carboxypeptidase
- Penicillin-Binding Proteins
- Peptidyl Transferases
- Phenotype
- Staphylococcus