Article
L-selectin gene polymorphisms in Graves' disease.
Clinical endocrinology - 1 Jul 2007
Chen Hao-Yan, Cui Bin, Wang Shu, Zhao Ze-Fei, Sun Hua, Zhao Yong-Ju, Li Xiao-Ying, Ning Guang
Abstract excerpt
OBJECTIVE: Graves' disease (GD) is an autoimmune disorder with genetic predisposition. There is strong evidence that members of the selectin family participate in the interaction between leucocytes and the endothelium, as well as in inflammatory cell recruitment. Moreover, a high serum level of a...
Topics
- Adolescent
- Adult
- Age of Onset
- Aged
- Aged, 80 and over
- Asian People
- Chi-Square Distribution
- Child
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Genotype
- Graves Disease
- Humans
- L-Selectin
- Male
- Middle Aged
- Odds Ratio