Article
Intercellular adhesion molecule 1 gene polymorphisms in Graves' disease.
The Journal of clinical endocrinology and metabolism - 1 Oct 2003
Kretowski Adam, Wawrusiewicz Natalia, Mironczuk Katarzyna, Mysliwiec Janusz, Kretowska Malgorzata, Kinalska Ida
Abstract excerpt
It was recently suggested that genetic factors could play a major role in the development of Graves' disease (GD). The aim of the present study was to evaluate the frequency of the c.721G-->A polymorphism and the c.1405A-->G polymorphism of the intercellular adhesion molecule 1 (ICAM-1) gene in subjects with GD compared with that in healthy controls, because ICAM-1 was found to play a key role in lymphocyte...
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