Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Lower specific micronutrient intake in colorectal cancer patients with tumors presenting promoter hypermethylation in p16(INK4a), p4(ARF) and hMLH1.

Anticancer research - 1 Jan 2000

Mas Sergi, Lafuente M Jose, Crescenti Anna, Trias Manuel, Ballesta Antonio, Molina Rafael, Zheng Shichun, Wiencke John K, Lafuente Amalia

Abstract excerpt

BACKGROUND: The diversity of the Mediterranean diet and the heterogeneity of acquired epigenetic alterations in colorectal cancer (CRC) led us to examine the possible association between dietary factors and promoter hypermethylation in genes implicated in the pathogenesis of these neoplasms (p16(...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptor Proteins, Signal Transducing
Share to Cyclin-Dependent Kinase Inhibitor p16

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Methylation

Share to Methylenetetrahydrofolate Reductase (NADPH2)

Share to Micronutrients

Share to MutL Protein Homolog 1

Share to Tumor Suppressor Protein p14ARF

Source

Identifiers

PMID: 17465256

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17465256-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lower specific micronutrient intake in colorectal cancer patients with tumors presenting promoter hypermethylation in p16(INK4a), p4(ARF) and hMLH1.PMID 17465256Read ↗

Associations of dietary methyl donor intake with MLH1 promoter hypermethylation and related molecular phenotypes in sporadic colorectal cancer.Semantic proximity Read ↗

Genetic variants of methyl metabolizing enzymes and epigenetic regulators: associations with promoter CpG island hypermethylation in colorectal cancer.Semantic proximity Read ↗

Aberrant DNA methylation of P16, MGMT, and hMLH1 genes in combination with MTHFR C677T genetic polymorphism and folate intake in esophageal squamous cell carcinoma.Semantic proximity Read ↗

B vitamins, methionine and alcohol intake and risk of colon cancer in relation to BRAF mutation and CpG island methylator phenotype (CIMP).Semantic proximity Read ↗

High levels of circulating folate concentrations are associated with DNA methylation of tumor suppressor and repair genes p16, MLH1, and MGMT in elderly ChileansSemantic proximity Read ↗

Relationships among folate, alcohol consumption, gene variants in one-carbon metabolism and p16INK4a methylation and expression in healthy breast tissuesSemantic proximity Read ↗

Decrease in specific micronutrient intake in colorectal cancer patients with tumors presenting Ki-ras mutation.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase C677T genotype affects promoter methylation of tumor-specific genes in sporadic colorectal cancer through an interaction with folate/vitamin B12 status.Semantic proximity Read ↗

Folate and related micronutrients, folate-metabolising genes and risk of ovarian cancer.Semantic proximity Read ↗

Dietary folate and related micronutrients, folate-metabolising genes, and ovarian cancer survival.Semantic proximity Read ↗

Dietary folate is associated with p16(INK4A) methylation in head and neck squamous cell carcinoma.Semantic proximity Read ↗

MTHFR, MTR, and MTRR polymorphisms in relation to p16INK4A hypermethylation in mucosa of patients with colorectal cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.