Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Protective role of connexin 32 in steady-state hematopoiesis, regeneration state, and leukemogenesis.

Experimental biology and medicine (Maywood, N.J.) - 1 May 2007

Hirabayashi Yoko, Yoon Byung-Il, Tsuboi Isao, Huo Yan, Kodama Yukio, Kanno Jun, Ott Thomas, Trosko James E, Inoue Tohru

Abstract excerpt

The role of gap junctions formed by connexins (Cxs) has been implicated in the homeostatic regulation of multicellular systems. Primitive hematopoietic progenitor cells form a multicellular system, but a previous report states that Cx32 is not expressed in the bone marrow. Thus, a question arises as to why Cx molecules are not detected in the hematopoietic tissue other than in stromal cells. Based on our...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Marrow Transplantation
Share to Connexins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fluorouracil

Share to Gap Junction beta-1 Protein

Share to Hematopoiesis

Share to Leukemia

Share to Methylnitrosourea

Share to Regeneration

Source

Identifiers

PMID: 17463168

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Protective role of connexin 32 in steady-state hematopoiesis, regeneration state, and leukemogenesis.PMID 17463168Read ↗

Bone marrow connexin-43 expression is critical for hematopoietic regeneration after chemotherapy.Semantic proximity Read ↗

A connexin/ifi30 pathway bridges HSCs with their niche to dampen oxidative stress.Semantic proximity Read ↗

Involvement of gap junctions in tumor suppression: analysis of genetically-manipulated mice.Semantic proximity Read ↗

The effect of connexin32 null mutation on hepatocarcinogenesis in different mouse strains.Semantic proximity Read ↗

Exacerbation of benzene pneumotoxicity in connexin 32 knockout mice: enhanced proliferation of CYP2E1-immunoreactive alveolar epithelial cells.Semantic proximity Read ↗

Delayed liver regeneration and increased susceptibility to chemical hepatocarcinogenesis in transgenic mice expressing a dominant-negative mutant of connexin32 only in the liver.Semantic proximity Read ↗

Altered homologous and heterologous gap-junctional intercellular communication in primary human liver tumors associated with aberrant protein localization but not gene mutation of connexin 32.Semantic proximity Read ↗

Connexins as targets for cancer chemoprevention and chemotherapy.Semantic proximity Read ↗

WY-14,643-mediated promotion of hepatocarcinogenesis in connexin32-wild-type and connexin32-null mice.Semantic proximity Read ↗

Role of connexin32 and beta-catenin in tumor promotion in mouse liver.Semantic proximity Read ↗

Connexin 32 dominant-negative mutant transgenic rats are resistant to hepatic damage by chemicals.Semantic proximity Read ↗

Titration of the gap junction protein Connexin43 reduces atherogenesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.