A 6 gene signature identifies the risk of developing cirrhosis in patients with chronic hepatitis B.

doi:10.2741/4403

Back to search

Article

A 6 gene signature identifies the risk of developing cirrhosis in patients with chronic hepatitis B.

Frontiers in bioscience (Landmark edition) - 1 Jan 2016

Xu Ming-Yi, Qu Ying, Li Zhenghong, Li Fei, Xiao Chun-Yang, Lu Lun-Gen

Abstract excerpt

Clinical factors and liver biopsy cannot accurately predict the risk of developing cirrhosis in chronic hepatitis B (CHB).This study was to develop a predictive gene signature for cirrhosis in CHB patients. A total of 183 untreated CHB patients were enrolled. GeneChip, significant analysis of mic...

Topics

Algorithms
Gene Expression Profiling
Genetic Predisposition to Disease
Hepatitis B, Chronic
Humans
Liver Cirrhosis
Risk Factors

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.