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Article

A 6 gene signature identifies the risk of developing cirrhosis in patients with chronic hepatitis B.

Frontiers in bioscience (Landmark edition) - 1 Jan 2016

Xu Ming-Yi, Qu Ying, Li Zhenghong, Li Fei, Xiao Chun-Yang, Lu Lun-Gen

Abstract excerpt

Clinical factors and liver biopsy cannot accurately predict the risk of developing cirrhosis in chronic hepatitis B (CHB).This study was to develop a predictive gene signature for cirrhosis in CHB patients. A total of 183 untreated CHB patients were enrolled. GeneChip, significant analysis of microarray (SAM) and prediction analysis of microarray (PAM) were used to select predictor genes (PGs) in liver tissues....

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26709788
DOI: 10.2741/4403

Genes

PAM
CXCL6
EHF
ITGBL1
LUM
SOX9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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