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Article

Genotyping of the cytochrome P450 2D6 4469 C>T polymorphism using SimpleProbes.

Scandinavian journal of clinical and laboratory investigation - 1 Jan 2007

Nielsen K A, Hansen E Lyders, Gille S

Abstract excerpt

BACKGROUND: Genotyping of human cytochrome P450s is a pharmacogenetic approach to diagnosing inherited deficiencies in drug metabolizing enzymes that influence therapeutic responses. The P450 CYP2D6 (debrisoquine hydroxylase) metabolizes numerous antidepressants and neuroleptic agents and there is evidence of a relationship between gene polymorphism and variant therapeutic response. Polymorphism in CYP2D6 causes...

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PMID: 17454842
DOI: 10.1080/00365510601039982

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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