Article
Central overexpression of angiotensin AT(1A) receptors prevents dopamine D(2) receptor regulation of alcohol consumption in mice.
Alcoholism, clinical and experimental research - 1 Jul 2007
Moore Rosanna, Krstew Elena V, Kirchhoff Jeppe, Davisson Robin L, Lawrence Andrew J
Abstract excerpt
BACKGROUND: While angiotensin receptors are found on the soma and terminals of dopaminergic neurons, controversy surrounds the potential role of angiotensin in alcohol consumption. METHODS: Using a transgenic mouse with a brain-specific overexpression of angiotensin AT(1A) receptors (NSE-AT(1A) mice), we have examined the role of angiotensin in alcohol consumption and alcohol-induced regulation of the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
