Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Alteration of catecholamine phenotype in transgenic mice influences expression of adrenergic receptor subtypes.

Journal of neurochemistry - 1 Aug 1995

Kobayashi K, Ota A, Togari A, Morita S, Mizuguchi T, Sawada H, Yamada K, Nagatsu I, Matsumoto S, Fujita K

Abstract excerpt

Agonist-induced regulation of adrenergic receptors (ARs) has an important role in controlling physiological functions in response to changes in catecholamine stimulation. We previously generated transgenic mice expressing phenylethanolamine N-methyltransferase (PNMT) under the control of a human dopamine beta-hydroxylase gene promoter to switch catecholamine specificity from the norepinephrine phenotype to the...

Topics

Animals
Axons
Biological Transport
Catecholamines
Epinephrine
Female
Humans
Lung
Male
Mice
Mice, Inbred C57BL
Mice, Transgenic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neurons

Phenotype

RNA, Messenger

Receptors, Adrenergic

Sympathetic Nervous System

Source

Identifiers

PMID: 7616202
DOI: 10.1046/j.1471-4159.1995.65020492.x

Genes

PNMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7616202-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Alteration of catecholamine phenotype in transgenic mice influences expression of adrenergic receptor subtypes.PMID 7616202Read ↗

Alteration of neurotransmitter phenotype in noradrenergic neurons of transgenic mice.Semantic proximity Read ↗

[Genetic conversion of neurotransmitter phenotype in transgenic mice].Semantic proximity Read ↗

Hypertension in transgenic mice with brain-selective overexpression of the alpha(2B)-adrenoceptor.Semantic proximity Read ↗

Hypotension, autonomic failure, and cardiac hypertrophy in transgenic mice overexpressing the alpha 1B-adrenergic receptor.Semantic proximity Read ↗

Transgenic mice carrying the human beta 2-adrenergic receptor gene with its own promoter overexpress beta 2-adrenergic receptors in liver.Semantic proximity Read ↗

?2-Adrenergic Receptor Subtypes ? Novel Functions Uncovered in Gene-Targeted Mouse ModelsSemantic proximity Read ↗

Targeting of the enhanced green fluorescent protein reporter to adrenergic cells in mice.Semantic proximity Read ↗

Autonomic neuropathy in transgenic mice caused by immunotoxin targeting of the peripheral nervous system.Semantic proximity Read ↗

Reduced sympathetic innervation after alteration of target cell neurotransmitter phenotype in transgenic mice.Semantic proximity Read ↗

Constitutive Activity of the Human β1-Adrenergic Receptor in β1-Receptor Transgenic MiceSemantic proximity Read ↗

Epinephrine is required for normal cardiovascular responses to stress in the phenylethanolamine N-methyltransferase knockout mouse.Semantic proximity Read ↗

PNMT transgenic mice have an aggressive phenotype.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.