Article
Trace Amine-Associated Receptor 1 Regulation of Methamphetamine Intake and Related Traits.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Aug 2015
Harkness John H, Shi Xiao, Janowsky Aaron, Phillips Tamara J
Abstract excerpt
Continued methamphetamine (MA) use is dependent on a positive MA experience and is likely attenuated by sensitivity to the aversive effects of MA. Bidirectional selective breeding of mice for high (MAHDR) or low (MALDR) voluntary consumption of MA demonstrates a genetic influence on MA intake. Quantitative trait locus (QTL) mapping identified a QTL on mouse chromosome 10 that accounts for greater than 50% of the...
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