Article
Association between physical activity and BMD in young men is modulated by catechol-O-methyltransferase (COMT) genotype: the GOOD study.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Aug 2007
Lorentzon Mattias, Eriksson Anna L, Nilsson Staffan, Mellström Dan, Ohlsson Claes
Abstract excerpt
UNLABELLED: In this large population-based study in young men, we show that the COMT val158met polymorphism modulates the association between physical activity, aBMD (DXA), and trabecular vBMD (pQCT). INTRODUCTION: Peak BMD is an important predictor of future risk of osteoporosis and is largely determined by genetic factors but also by environmental factors, among which physical activity (PA) is a strong...
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