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Article

Identification of microRNAs regulated by isothiocyanates and association of polymorphisms inside their target sites with risk of sporadic colorectal cancer.

Nutrition and cancer - 1 Jan 2013

Slaby Ondrej, Sachlova Milana, Brezkova Veronika, Hezova Renata, Kovarikova Alena, Bischofová Svatava, Sevcikova Sabina, Bienertova-Vasku Julie, Vasku Anna, Svoboda Marek, Vyzula Rostislav

Abstract excerpt

Sporadic colorectal cancer (CRC) is a typical multifactorial disease. Isothiocyanates (ITC) have been recently shown to inhibit development of CRC in many experimental models. MicroRNAs (miRNAs) are short noncoding RNAs that posttranscriptionally regulate gene expression through binding to 3' untranslated regions (3'UTR) of target mRNAs. MiRNAs are regulated by natural agents, ITCs included. In our study, using...

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Identifiers

PMID: 23441612
DOI: 10.1080/01635581.2013.756530

Genes

DICER1
ADAM19
AGTR1
HSPA9
PRKCB
RABGAP1
SIRT5
TNFAIP2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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