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Cancer Familial Aggregation (CFA) and G446A polymorphism in ARLTS1 gene.

Breast cancer research and treatment - 1 Sept 2006

Masojć Bartłomiej, Mierzejewski Marek, Cybulski Cezary, van de Wetering Thierry, Debniak Tadeusz, Górski Bohdan, Jaworowska Ewa, Tarnowska Czesława, Lenner Marcin, Scott Rodney J, Lubiński Jan

Abstract excerpt

ARLTS1--a member of ADP-ribosylation factor family, is a newly described candidate tumour suppressor gene. Recent studies show that a nonsense polymorphism, G446A (Trp149Stop), in ARLTS1 gene is significantly more frequent in familial cancer cases than in sporadic cancer cases. This study presents analysis of the germ-line G446A polymorphism in the ARLTS1 gene among 1686 consecutively collected patients with...

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PMID: 16570116
DOI: 10.1007/s10549-006-9180-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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