Article
Relationship between ARLTS1 polymorphisms and risk of chronic lymphocytic leukemia.
Leukemia research - 1 Dec 2006
Sellick Gabrielle S, Catovsky Daniel, Houlston Richard S
Abstract excerpt
ARLTS1, a member of the Ras superfamily and putative tumor-suppressor gene resides at chromosome 13q14, a region commonly deleted in hematopoietic and solid tumors. Previously, the truncating single nucleotide polymorphism (SNP) of ARLTS, G446A (W149X) has been reported to act as a multi-site tumor susceptibility allele. To explore the relationship between polymorphic variation in ARTLS1 and risk of chronic...
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