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Article

Interaction of Epe1 with the heterochromatin assembly pathway in Schizosaccharomyces pombe.

Genetics - 1 Apr 2007

Isaac Sara, Walfridsson Julian, Zohar Tal, Lazar David, Kahan Tamar, Ekwall Karl, Cohen Amikam

Abstract excerpt

Epe1 is a JmjC domain protein that antagonizes heterochromatization in Schizosaccharomyces pombe. Related JmjC domain proteins catalyze a histone demethylation reaction that depends on Fe(II) and alpha-ketoglutarate. However, no detectable demethylase activity is associated with Epe1, and its JmjC domain lacks conservation of Fe(II)-binding residues. We report that Swi6 recruits Epe1 to heterochromatin and that...

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Share to Chromatin Assembly and Disassembly
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17449867
DOI: 10.1534/genetics.106.068684
PMCID: PMC1855143

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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