Article
Structure-based functional analysis of the replication protein of plasmid R6K: key amino acids at the pi/DNA interface.
Journal of bacteriology - 1 Jul 2007
Kunnimalaiyaan Selvi, Rakowski Sheryl A, Filutowicz Marcin
Abstract excerpt
In previous work, we characterized the bases in an iteron of plasmid R6K that are important for the binding of pi protein monomers and dimers. Here we investigate the following six amino acids of pi, encoded by pir, hypothesized to be important for DNA contact: Ser71, Try74, Gly131, Gly211, Arg225, and Arg254.
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