Article
Imprinting and expression analysis of a non-coding RNA gene in the mouse Dlk1-Dio3 domain.
Journal of molecular histology - 1 Aug 2011
Zhang Feng Wei, Zeng Tie Bo, Han Zheng Bin, He Hong Juan, Chen Yan, Gu Ning, Jiang Hui Jie, Wu Qiong
Abstract excerpt
The Dlk1-Dio3 imprinted domain not only is implicated growth and development of the embryo and placenta, but also affects adult metabolism and brain function. In this study, we identified the imprinting status of a mouse non-coding RNA gene, B830012L14Rik, mapped to the Dlk1-Dio3 domain by the polymorphism- and sequencing-based approach. Imprinting analysis showed that the gene was expressed maternally at E15.5,...
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