Article
Multiple genes for essential-hypertension susceptibility on chromosome 1q.
American journal of human genetics - 1 Feb 2007
Chang Yen-Pei Christy, Liu Xin, Kim James Dae Ok, Ikeda Morna A, Layton Marnie R, Weder Alan B, Cooper Richard S, Kardia Sharon L R, Rao D C, Hunt Steve C, Luke Amy, Boerwinkle Eric, Chakravarti Aravinda
Abstract excerpt
Essential hypertension, defined as elevated levels of blood pressure (BP) without any obvious cause, is a major risk factor for coronary heart disease, stroke, and renal disease. BP levels and susceptibility to development of essential hypertension are partially determined by genetic factors that are poorly understood. Similar to other efforts to understand complex, non-Mendelian phenotypes, genetic dissection of...
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