Article
Association of alpha1A adrenergic receptor gene variants on chromosome 8p21 with human stage 2 hypertension.
Journal of hypertension - 1 Jun 2006
Gu Dongfeng, Ge Dongliang, Snieder Harold, He Jiang, Chen Shufeng, Huang Jianfeng, Li Biao, Chen Runsheng, Qiang Boqin
Abstract excerpt
OBJECTIVE AND DESIGN: We previously reported a significant linkage between human chromosome 8p22 with essential hypertension and systolic blood pressure levels. On the basis of this, we used an efficient age, sex and area-matched case-control scheme to test the association of the polymorphisms in the human alpha1A adrenergic receptor (ADRA1A) gene, located on chromosome 8p21-p11.2, with essential hypertension in...
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