Article
Association of ATP1B1 single-nucleotide polymorphisms with blood pressure and hypertension in a Chinese population.
Clinica chimica acta; international journal of clinical chemistry - 1 Sept 2009
Xiao Bing, Zhang Yi, Niu Wenquan, Gao Pinjing, Zhu Dingliang
Abstract excerpt
BACKGROUND: ATP1B1 encodes the beta subunits of Na/K ATPase which plays an important role in maintaining the normal gradients of Na(+) and K(+) across plasma membrane. A recent study demonstrated an association of ATP1B1 genetic variations with blood pressure (BP) in Americans. We aimed to investigate the association between ATP1B1 polymorphisms with BP and hypertension in a Chinese population. MATERIAL AND...
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