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Article

Association of IL-10 receptor 2 (IL10RB) SNP with systemic sclerosis.

Biochemical and biophysical research communications - 29 Aug 2008

Hikami Koki, Ehara Yukikazu, Hasegawa Minoru, Fujimoto Manabu, Matsushita Masaki, Oka Takanori, Takehara Kazuhiko, Sato Shinichi, Tokunaga Katsushi, Tsuchiya Naoyuki

Abstract excerpt

Interleukin-10 (IL-10) signaling has been suggested to play a role in systemic sclerosis (SSc). IL10RB codes for IL-10 receptor 2 (IL-10R2), a component shared in receptor complexes for IL-10, IL-22, IL-26 and interferon (IFN)-lambda. In this study, we examined association of IL10RB polymorphism with susceptibility to SSc. Genotype A/A at rs2834167 (47K/K) was significantly increased in diffuse cutaneous SSc...

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Identifiers

PMID: 18588853
DOI: 10.1016/j.bbrc.2008.06.054

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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