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Article

Association of IL1A gene polymorphisms with susceptibility to and severity of systemic sclerosis in the Japanese population.

Arthritis and rheumatism - 1 Jan 2003

Kawaguchi Yasushi, Tochimoto Akiko, Ichikawa Naomi, Harigai Masayoshi, Hara Masako, Kotake Shigeru, Kitamura Yutaka, Kamatani Naoyuki

Abstract excerpt

OBJECTIVE: To analyze the frequencies of haplotypes of single-nucleotide polymorphisms (SNPs) of the IL1A gene (at -889, +4729, and +4845) in patients with systemic sclerosis (SSc) and in healthy control subjects, and to determine whether the IL1A gene haplotype is associated with SSc susceptibility or disease severity. METHODS: We studied 60 patients with SSc (34 with diffuse cutaneous SSc and 26 with limited...

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PMID: 12528118
DOI: 10.1002/art.10736

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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