Article
Detecting disease gene in DNA haplotype sequences by nonparametric dissimilarity test.
Human genetics - 1 Sept 2006
Yuan Ao, Yue Qingqi, Apprey Victor, Bonney George
Abstract excerpt
Association studies for complex diseases based on haplotype data have received increasing attention in the last few years. A commonly used nonparametric method, which takes haplotype structure into consideration, is to use the U-statistic to compare the similarities between genetic compositions in the case and control populations. Although the method and its variants are convenient to use in practice, there are...
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