Characterization of spleen colonies derived from mice with mutations at the W locus.

doi:10.1002/jcp.1041490314

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Article

Characterization of spleen colonies derived from mice with mutations at the W locus.

Journal of cellular physiology - 1 Dec 1991

Barker J E, Starr E

Abstract excerpt

Mice with mutations at the W locus have a hemopoietic stem cell defect characterized by an apparent deficiency of spleen colony forming cells (CFU-S). In the present report, we provide evidence that mutant cells form colonies and we compare the characteristics of the colonies derived from mutant...

Topics

Animals
Bone Marrow Transplantation
Colony-Forming Units Assay
Genetic Markers
Glucose-6-Phosphate Isomerase
Granulocytes
Hematopoietic Stem Cells
Megakaryocytes
Mice
Mice, Inbred C57BL
Mice, Mutant Strains
Mutation
Spleen

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