Article
Characterization of spleen colonies derived from mice with mutations at the W locus.
Journal of cellular physiology - 1 Dec 1991
Barker J E, Starr E
Abstract excerpt
Mice with mutations at the W locus have a hemopoietic stem cell defect characterized by an apparent deficiency of spleen colony forming cells (CFU-S). In the present report, we provide evidence that mutant cells form colonies and we compare the characteristics of the colonies derived from mutant and normal cells. To perform the colony-derivation studies, marrow cells were transferred into lethally irradiated...
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