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Article

Disruption of the homeobox gene Hoxb-6 in mice results in increased numbers of early erythrocyte progenitors.

American journal of hematology - 1 Oct 2000

Kappen C

Abstract excerpt

Hox genes encode transcription factors that are required for proper development of certain tissues and for patterning of the hindbrain, the limbs, and skeleton. They are also expressed in the hematopoietic system with a preference for specific cell lineages. To determine the role of Hoxb-6 in normal hematopoiesis, mice with a targeted disruption in the Hoxb-6 gene were generated. Mature hematopoietic cell types...

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Identifiers

PMID: 10996827
DOI: 10.1002/1096-8652(200010)65:2<111::aid-ajh4>3.0.co;2-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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