Article
Hematopoietic stem cells in +/+, nu/+, and nu/nu C57Bl/10 mice.
Experimental hematology - 1 Aug 1991
Necas E, Znojil V, Holub M
Abstract excerpt
Mice with the nu mutation have been shown to have a reduced incidence of spleen colony-forming units (CFU-S), with a higher variability between individual mice compared to +/+ mice. The presence of these defects also in nu/+ mice indicates that this mutation is a codominant trait and that the hematopoietic changes may not be solely caused by thymus dysgenesis. The proportion of CFU-S synthesizing DNA...
Topics
- Animals
- Body Weight
- Bone Marrow Cells
- DNA
- Hematopoietic Stem Cells
- Heterozygote
- Mice
- Mice, Inbred C57BL
- Mice, Nude
- Mutation
- Spleen