Article
Identification of novel factors which bind specifically to the core promoter of the immunoglobulin heavy chain gene.
The Journal of biological chemistry - 5 Dec 1991
Parvin J D, Sharp P A
Abstract excerpt
Nuclear extracts from HeLa cells and the B-cell line, BJA-B, generated two protein-DNA complexes which bound specifically to sequences in the TATA box of the immunoglobulin heavy chain gene (IgH) promoter. Complex A also bound the core promoter of a retroviral long terminal repeat but did not bin...
Topics
- Base Sequence
- Binding, Competitive
- DNA
- DNA-Binding Proteins
- Gene Expression Regulation
- HeLa Cells
- Humans
- Immunoglobulin Heavy Chains
- Molecular Sequence Data
- Mutation
- Promoter Regions, Genetic
- RNA, Messenger
- TATA Box
- Transcription, Genetic