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Article

Transcriptional regulation of precore and pregenomic RNAs of hepatitis B virus

1 Jul 1992

Abstract excerpt

Hepatitis B virus (HBV) infection, either acute or chronic, has been one of the leading health problems in the world. To understand the HBV life cycle and disease process, we set out to study the regulation of viral gene expression. In this paper, we report the characterization of the HBV core promoter: two 3.5-kb transcripts, precore and pregenomic, are made from it. The latter is itself a template for viral...

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PMID: 1602534
DOI: 10.1128/jvi.66.7.4073-4084.1992

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